Canon RF 100–400mm F5.6–8 IS USM vs Canon RF 75–300mm F4–5.6

Every spec side by side, from each maker's published figures.

Better figure, where one is clearly better

RF 100–400mm F5.6–8 IS USM compared with RF 75–300mm F4–5.6
CanonRF 100–400mm F5.6–8 IS USMCanonRF 75–300mm F4–5.6
Overview
ReleasedOctober 2021May 2025
Optics
Lens typeZoomZoom
Focal length100–400 mm75–300 mm
Maximum aperturef/5.6–8f/4–5.6
Minimum aperturef/32–45f/32–45
Optical construction12 elements in nine groupsThirteen elements in nine groups; Canon states the optical design is adapted from the EF 75–300mm F4–5.6 III
Special elementsOne UD element and one PMo aspherical element–
CoatingsSuper Spectra; no fluorine coating, per UK maker tableSuper Spectra; no fluorine coating
Aperture detail–Maximum f/4 at 75 mm and f/5.6 at 300 mm; minimum f/32 and f/45 respectively
DiaphragmNine bladesSeven blades
Angle of view–Full-frame diagonal 32°11′–8°15′; horizontal 27°–6°50′; vertical 18°11′–4°35′
Mount and compatibility
MountsCanon RFCanon RF
Image circleFull frameFull frame
CompatibilityCanon RF mount, full-frame image circle; incompatible with EF DSLRs and EOS M camerasCanon RF mount for full-frame and APS-C EOS R cameras; 120–480 mm equivalent field of view on Canon APS-C
Teleconverter supportRF1.4× gives 140–560 mm f/8–11 and maximum 0.58×; RF2× gives 200–800 mm f/11–16 and maximum 0.83×. Maker confirms autofocus and IS, with reduced AF coverage on listed EOS R bodies; extenders usable throughout the zoom rangeNot compatible with RF extenders (The-Digital-Picture)
Focus and stabilisation
AutofocusYesYes
Minimum focus distance0.88 m1.5 m
Maximum magnification0.41×0.25×
Optical stabilisationYesNo
Autofocus detailNano USM autofocus and electronic manual focusDC motor autofocus; no full-time manual focus override (Digital Camera World)
Focus distance detailMaker minimum focus 1.2 m at 100 mm, 0.88 m at 200 mm, 0.95 m at 300 mm and 1.05 m at 400 mm. Main value is the closest published distance at 200 mm; Cameralabs’ approximate constant-distance observation does not replace the maker’s per-focal-length table1.5 m minimum focus; front element and focus ring rotate during focusing (Digital Camera World and The-Digital-Picture)
Magnification detail0.09× at 100 mm, 0.24× at 200 mm, 0.34× at 300 mm and 0.41× at 400 mm; no unpublished AF/MF distinction inferred0.06× at 75 mm and 0.25× at 300 mm
Stabilisation detailOptical IS rated 5.5 stops at 400 mm on EOS R under CIPA, yaw/pitch; coordinated EOS R5 body/lens IS rated six stops under the same maker conditions. Cameralabs measured approximately five stops at 100 mm and three at 400 mm with EOS R6, a different test conditionNo lens optical stabilisation
Video featuresCameralabs found little focus breathing and mostly maintained focus while zooming in its tests; these are reviewer observations rather than maker parfocal certificationSubstantial focus breathing in The-Digital-Picture's test
Design
Dust and moisture resistantNo–
Filter diameter67 mm58 mm
Maximum diameter79.5 mm71.2 mm
Length164.7 mm146.1 mm
Weight635 g507 g (better)
ControlsSeparate zoom, electronic manual focus and custom control rings; AF/MF and IS switches; zoom lockManual focus and zoom rings, AF/MF switch; no custom control ring (The-Digital-Picture)
Zoom designExtending zoom barrel; main maker length measured retractedExtending zoom barrel; further extension and front rotation during focusing (Digital Camera World)
Filter detail–58 mm front thread rotates during focusing
Weather resistanceUK maker specification explicitly states no dust/moisture resistanceCanon UK's table lists dust/moisture resistance, but Digital Camera World and The-Digital-Picture both report no weather sealing
Dimensions detailApproximately 79.5 mm maximum diameter × 164.7 mm length when retracted71.2 mm maximum diameter × 146.1 mm retracted length
Weight detailApproximately 635 g lensApproximately 507 g lens
Lens hoodET-74B, optional accessoryOptional ET-60 hood, not included
In the box–Lens, E-58 II lens cap, RF dust cap and user manual
Release detailOctober 2021 marketed month in Canon Camera Museum, matching Canon Canada’s original October availability. No exact worldwide first-sale day inferred; no direct replacement of brighter EF or RF L-series zooms assumedMay 2025 release confirmed retrospectively by Canon's February 2026 press release and Canon Camera Museum

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